BDBM370866 2-cyclopropyl-N-ethyl-N-{2-[5-(1- hydroxy-1-methylethyl)pyridin-2- yl]ethyl}benzamide::US10239838, Example 60

SMILES CCN(CCc1ccc(cn1)C(C)(C)O)C(=O)c1ccccc1C1CC1

InChI Key InChIKey=UXIHNKZMGBITRV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 370866   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM370866(US10239838, Example 60 | 2-cyclopropyl-N-ethyl-N-{...)
Affinity DataIC50: 244nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM370866(US10239838, Example 60 | 2-cyclopropyl-N-ethyl-N-{...)
Affinity DataIC50: 1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent