BDBM370832 N-ethyl-N-(2-(6-(2-hydroxypropan-2- yl)pyridin-2-yl)ethyl)-2-(2,2,2- trifluoroethoxy)benzamide::US10239838, Example 17

SMILES CCN(CCc1cccc(n1)C(C)(C)O)C(=O)c1ccccc1OCC(F)(F)F

InChI Key InChIKey=TVFYVGJCTXKANW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 370832   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM370832(US10239838, Example 17 | N-ethyl-N-(2-(6-(2-hydrox...)
Affinity DataIC50: 261nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM370832(US10239838, Example 17 | N-ethyl-N-(2-(6-(2-hydrox...)
Affinity DataIC50: 1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent