BDBM370815 US10239835, Example 00366::US20240199576, Example 10 from WO 2016/049165

SMILES [H][C@@]1(C[C@]2([H])CN(C[C@H](O)c3ccc(O)cn3)C[C@]2([H])C1)Oc1ccccc1F

InChI Key InChIKey=NEFQLCKWVRZEJA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 370815   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Cadent Therapeutics

US Patent
LigandPNGBDBM370815(US10239835, Example 00366 | US20240199576, Example...)
Affinity DataIC50: 8.30nMAssay Description:Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
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LigandPNGBDBM370815(US10239835, Example 00366 | US20240199576, Example...)
Affinity DataIC50: 2.30E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
Go to US Patent