BDBM370608 (S)-(3-Hydroxypiperidin-1-yl)(4-(4-(((5-methoxy-2-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)benzo[d]thiazol-7-yl)oxy)methyl)-5-methylthiazol-2-yl)phenyl)methanone::US10238638, Example 38

SMILES COc1cc(OCc2nc(sc2C)-c2ccc(cc2)C(=O)N2CCC[C@H](O)C2)c2sc(nc2c1)-c1cn2nc(C)sc2n1

InChI Key InChIKey=RGKFCHNKVUXZEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370608   

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM370608(US10238638, Example 38 | (S)-(3-Hydroxypiperidin-1...)
Affinity DataIC50: 1.60E+3nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
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Date in BDB:
12/30/2019
Entry Details
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