BDBM370585 US10238638, Example 14

SMILES COc1cc(OCc2csc(n2)-c2ccc(cc2)C(O)=O)c2sc(nc2c1)-c1cn2nc(sc2n1)C(C)(F)F

InChI Key InChIKey=OGIQORFYSSDKIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370585   

TargetPRKC apoptosis WT1 regulator protein(Human)
Universite De Montreal

US Patent
LigandPNGBDBM370585(US10238638, Example 14)
Affinity DataIC50: 8.70E+4nMAssay Description:The FLIPR assay is an exemplary in vitro assay for measuring the activity of the PAR4 antagonists of the present invention. In this assay, intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
Go to US Patent