BDBM370528 (2S)-2-amino-1-(4-(1-hydroxy-2-(5H- imidazo[5,1-a]isoindol-5-yl)ethyl)piperidin-1- yl)-3-phenylpropan-1-one::US10233190, Example 1451

SMILES N[C@@H](Cc1ccccc1)C(=O)N1CCC(CC1)C(O)CC1c2ccccc2-c2cncn12

InChI Key InChIKey=KVZKINKUBBROSQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370528   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandPNGBDBM370528((2S)-2-amino-1-(4-(1-hydroxy-2-(5H- imidazo[5,1-a]...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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