BDBM370513 4-(1-hydroxy-2-(5H-imidazo[5,1-a]isoindol-5- yl)ethyl)-N-(2-(methylsulfonamido)ethyl) cyclohexanecarboxamide::US10233190, Example 1432

SMILES CS(=O)(=O)NCCNC(=O)C1CCC(CC1)C(O)CC1c2ccccc2-c2cncn12

InChI Key InChIKey=VJRHMPFUEKSHGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370513   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandPNGBDBM370513(4-(1-hydroxy-2-(5H-imidazo[5,1-a]isoindol-5- yl)et...)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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