BDBM370365 US10233189, Example 46

SMILES CC(CF)n1nc(C(=O)Nc2cc(C)[nH]n2)c2c(N)ncnc12

InChI Key InChIKey=OZKIFNJBOODRNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370365   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM370365(US10233189, Example 46)
Affinity DataIC50: 0.480nMAssay Description:To measure the inhibitory activity, first, the compounds of the present invention were individually diluted with dimethyl sulfoxide (DMSO) stepwise. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent