BDBM370083 US10233187, Example 21

SMILES CCCc1n[nH]c2c1C(C)(C)CN(C=C2C(=O)OC(C)C)C(=O)c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=WTUZXMGHEJRCEV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370083   

TargetBile acid receptor(Human)
Akarna Therapeutics

US Patent
LigandPNGBDBM370083(US10233187, Example 21)
Affinity DataEC50:  600nMAssay Description:Starting from 3.33 mM of compound in DMSO solution, a 10-point 3-fold serial dilution was made by diluting 5 μL of compound into 10 μL of D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent