BDBM370064 (E)-ethyl 6-(3,4-difluorobenzoyl)-3,4,4-trimethyl-1,4,5,6-tetrahydropyrazolo[3,4-d]azepine-8-carboxylate ::US10233187, Example 2

SMILES CCOC(=O)C1=CN(CC(C)(C)c2c(C)n[nH]c12)C(=O)c1ccc(F)c(F)c1

InChI Key InChIKey=WOYKZRIYRUHHEO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370064   

TargetBile acid receptor(Human)
Akarna Therapeutics

US Patent
LigandPNGBDBM370064((E)-ethyl 6-(3,4-difluorobenzoyl)-3,4,4-trimethyl-...)
Affinity DataEC50: <200nMAssay Description:Starting from 3.33 mM of compound in DMSO solution, a 10-point 3-fold serial dilution was made by diluting 5 μL of compound into 10 μL of D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent