BDBM370036 (R)-3-Chloro-N-(3-methyl-1-(3-methyl-1-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxobutan-2-yl)-5-(trifluoromethyl)benzamide::US10233182, Example 207

SMILES CC(C)[C@@H](NC(=O)c1cc(Cl)cc(c1)C(F)(F)F)C(=O)N1CCC2(CC1)N(CN(C)C2=O)c1ccc(=O)n(C)c1

InChI Key InChIKey=FLHHNKLGKZDSCR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370036   

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM370036((R)-3-Chloro-N-(3-methyl-1-(3-methyl-1-(1-methyl-6...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent