BDBM369955 (R)-2-Fluoro-N-(1-(1-(4-methoxybenzyl)-3-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-3-methyl-1-oxobutan-2-yl)-5-(trifluoromethyl)benzamide::US10233182, Example 91

SMILES COc1ccc(CN2C(=O)N(C)C(=O)C22CCN(CC2)C(=O)[C@H](NC(=O)c2cc(ccc2F)C(F)(F)F)C(C)C)cc1

InChI Key InChIKey=QQXOMARFNQGCBI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369955   

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369955((R)-2-Fluoro-N-(1-(1-(4-methoxybenzyl)-3-methyl-2,...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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