BDBM369928 5-Ethyl-2-fluoro-N-((2R,3S)-3-methoxy-1-(3-methyl-2,4-dioxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxobutan-2-yl)benzamide::US10233182, Example 37

SMILES CCc1ccc(F)c(c1)C(=O)N[C@H]([C@H](C)OC)C(=O)N1CCC2(CC1)N(C(=O)N(C)C2=O)c1ccccc1

InChI Key InChIKey=CAMLYXXGGGUBTP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369928   

TargetAutotaxin(Human)
X-Rx

US Patent
LigandPNGBDBM369928(5-Ethyl-2-fluoro-N-((2R,3S)-3-methoxy-1-(3-methyl-...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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