BDBM369696 US10233156, Example I-236::US20250041279, Compound I-11

SMILES C[C@@H](CCC1OC[C@@H](CO1)Oc1nc2c(F)cc(OCC(F)F)c(F)c2n1C)NC(N)=O

InChI Key InChIKey=CGSFGBCBMSRNPS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 369696   

TargetAcetyl-CoA carboxylase 2(Human)
Shionogi

US Patent
LigandPNGBDBM369696(US10233156, Example I-236 | US20250041279, Compoun...)
Affinity DataIC50: 9.60nMAssay Description:Recombinant human ACC1 and recombinant human ACC2, which were prepared by the method mentioned above, were preincubated with assay buffer solution (5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1(Human)
Shionogi

US Patent
LigandPNGBDBM369696(US10233156, Example I-236 | US20250041279, Compoun...)
Affinity DataIC50: 7.00E+3nMAssay Description:The recombinant human ACC1 and the recombinant human ACC2 obtained from the above Preparation Examples were preincubated in an assay buffer (50 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2025
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Shionogi

US Patent
LigandPNGBDBM369696(US10233156, Example I-236 | US20250041279, Compoun...)
Affinity DataIC50: 9.60nMAssay Description:The recombinant human ACC1 and the recombinant human ACC2 obtained from the above Preparation Examples were preincubated in an assay buffer (50 mM HE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2025
Entry Details
Go to US Patent