BDBM369594 US10233152, Example 105

SMILES O=C1Cc2cc(OCCN3CCC(CC3)N[C@@H]3C[C@H]3c3ccccc3)ccc2N1

InChI Key InChIKey=HMQWVKVFQCCFDI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369594   

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandPNGBDBM369594(US10233152, Example 105)
Affinity DataIC50: 6nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent