BDBM369478 N,N-Dimethyl-2-(4-(2-(4-(((1R,2S)-2-phenylcyclopropyl)amino)piperidin-1-yl)ethoxy)phenyl)acetamide d-hydrochloride (62) and N-methoxy-2-(4-(2-(4-(((1R,2S)-2-phenylcyclopropyl)amino)piperidin-1-yl)ethoxy)phenyl)acetamide (64)::US10233152, Example 18::US10233152, Example 19

SMILES CONC(=O)Cc1ccc(OCCN2CCC(CC2)N[C@@H]2C[C@H]2c2ccccc2)cc1

InChI Key InChIKey=XFKIGOCIXUBEIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 369478   

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandPNGBDBM369478(N,N-Dimethyl-2-(4-(2-(4-(((1R,2S)-2-phenylcyclopro...)
Affinity DataIC50: 7nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Mirati Therapeutics

US Patent
LigandPNGBDBM369478(N,N-Dimethyl-2-(4-(2-(4-(((1R,2S)-2-phenylcyclopro...)
Affinity DataIC50: 3nMAssay Description:Briefly, compounds of the present invention were solubilized in DMSO and a series of 10, three-fold serial dilutions were made for each compound in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent