BDBM3694 2-N-methyl-8-N-(3-methylphenyl)-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine::4-anilinopyrimido[5,4-d]pyrimidine deriv. 6c::6-(Methylamino)-4-[(3-methylphenyl)amino]pyrimido-[5,4-d]pyrimidine

SMILES CNc1ncc2ncnc(Nc3cccc(C)c3)c2n1

InChI Key InChIKey=CKGJCAISFNGPHH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3694   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3694(2-N-methyl-8-N-(3-methylphenyl)-[1,3]diazino[5,4-d...)
Affinity DataIC50: 4.30nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3694(2-N-methyl-8-N-(3-methylphenyl)-[1,3]diazino[5,4-d...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed