BDBM369398 4-[6-(4-fluorophenyl)-7H-pyrrolo[2,3- d]pyrimidin-4-yl]-2,2-dimethyl-N-[(1S)-1- (p-tolyl)ethyl]piperazine-1-carboxamide::US10227357, Compound P-0719

SMILES CNc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(N2CC3CCC(C2)N3C(=O)C[C@H](NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(F)CC2)C(C)(C)C)c2ccc(-c3scnc3C)cc2)s1

InChI Key InChIKey=NTXGLQZJANWUQF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369398   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369398BDBM369398(US12528814, Example 180)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent