BDBM369395 N-[(1S)-1-(4-chlorophenyl)ethyl]-4-[6-(1,3- dimethylpyrazol-4-yl)-7H-pyrrolo[2,3- d]pyrimidin-4-yl]piperazine-1- carboxamide::US10227357, Compound P-0716

SMILES N#Cc1cnn2c(-c3cc(NC)c(-c4nnc(N5CC6(CCN(C(=O)CN7CCN(c8ccc9c(c8)C(=O)N(C8CCC(=O)NC8=O)C9=O)CC7)CC6)C5)s4)cn3)ccc2c1

InChI Key InChIKey=LMLSIVBPIZQRAG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369395   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369395BDBM369395(US12528814, Example 177)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent