BDBM369386 4-[6-(4-fluorophenyl)thieno[3,2- d]pyrimidin-4-yl]-N-[1-(5-methyl-2- thienyl)ethyl]piperazine-1-carboxamide::US10227357, Compound P-0703

SMILES N#Cc1cnn2c(-c3cc(NC)c(-c4nnc([C@H]5CC[C@H](N(C)C(=O)C6CCN(c7ccc8c(c7)C(=O)N(C7CCC(=O)NC7=O)C8=O)CC6)CC5)s4)cn3)ccc2c1

InChI Key InChIKey=RGMZMROOQGKZFI-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369386   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369386BDBM369386(US12528814, Example 169)
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent