BDBM369384 (2R)-N-[(1S)-1-(3-chlorophenyl)ethyl]-4-[6- (4-fluorophenyl)-7H-pyrrolo[2,3- d]pyrimidin-4-yl]-2-methyl-piperazine-1- carboxamide::US10227357, Compound P-0701

SMILES CNc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc([C@H]2CC[C@H](N(C)CC3CCN(c4ccc(C(=O)NC5CCC(=O)NC5=O)nc4)CC3)CC2)s1

InChI Key InChIKey=ZTIFYAJIJPNSDX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369384   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369384BDBM369384(US12528814, Example 167)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent