BDBM369381 4-[6-(4-cyanophenyl)-7H-pyrrolo[2,3- d]pyrimidin-4-yl]-N-[(1S)-1-[3- (difluoromethoxy)phenyl]ethyl]-2,2- dimethyl-piperazine-1-carboxamide::US10227357, Compound P-0698

SMILES CNc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(N2CC3CCC(C2)N3C2CCN(C(=O)Cc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)CC2)s1

InChI Key InChIKey=QSPXMECUEVZEOM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369381   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369381BDBM369381(US12528814, Example 164)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent