BDBM369379 4-[6-(4-cyanophenyl)-7H-pyrrolo[2,3- d]pyrimidin-4-yl]-N-[(1S)-1-(4- fluorophenyl)ethyl]piperazine-1- carboxamide::US10227357, Compound P-0696

SMILES N#Cc1cnn2c(-c3cc(NC)c(C4=NN=C(N5CC6CCC(C5)N6C5CCN(C(=O)c6ccc7c(c6)C(=O)N(C6CCC(=O)NC6=O)C7)CC5)C4)cn3)ccc2c1

InChI Key InChIKey=QNMGSKCRRFIKSQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369379   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369379BDBM369379(US12528814, Example 162)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent