BDBM369348 N-[1-[6-(2,4-dimethylthiazol-5-yl)-7H- pyrrolo[2,3-d]pyrimidin-4-yl]-4- piperidyl]-4- (trifluoromethoxy)benzenesulfonamide::US10227357, Compound P-0664

SMILES N#Cc1cnn2c(-c3cc(NC)c(-c4nnc(N5CCN(C6CCN(C(=O)c7ccc(C(=O)NC8CCC(=O)NC8=O)cc7)CC6)CC5)s4)cn3)ccc2c1

InChI Key InChIKey=YACKSJVPNYSGIG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369348   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369348BDBM369348(US12528814, Example 132)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent