BDBM369326 N-[(1S)-1-(4-fluorophenyl)ethyl]-4-[6-(4- fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4- yl]-2,2-dimethyl-piperazine-1-carboxamide::US10227357, Compound P-0642

SMILES CNc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(C23CCC(NC(=O)CCOCCOCCOCCNc4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)(CC2)CC3)s1

InChI Key InChIKey=WUUTYTXLEXVJHY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369326   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369326BDBM369326(US12528814, Example 110)
Affinity DataIC50: 0.700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent