BDBM3693 4-anilinopyrimido[5,4-d]pyrimidine deriv. 6b::6-Amino-4-[(3-methylphenyl)amino]pyrimido[5,4-d]pyrimidine::8-N-(3-methylphenyl)-[1,3]diazino[5,4-d]pyrimidine-2,8-diamine

SMILES Cc1cccc(Nc2ncnc3cnc(N)nc23)c1

InChI Key InChIKey=OLZKKHBEDMOWRD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3693   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3693(6-Amino-4-[(3-methylphenyl)amino]pyrimido[5,4-d]py...)
Affinity DataIC50: 17nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3693(6-Amino-4-[(3-methylphenyl)amino]pyrimido[5,4-d]py...)
Affinity DataIC50: 17nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed