BDBM369293 6-(1,3-dimethylpyrazol-4-yl)-4-(4- piperidyl)thieno[3,2-d]pyrimidine::US10227357, Compound P-0607

SMILES N#Cc1cnn2c(-c3cc(NC(C)C)c(-c4nnc(N5CCN(C6CCN(C(=O)c7ccc8c(c7)C(=O)N(C7CCC(=O)NC7=O)C8)CC6)CC5)s4)cn3)ccc2c1

InChI Key InChIKey=BXQPNKQCBWXZOB-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369293   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369293BDBM369293(US12528814, Example 77)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent