BDBM369292 (2R)-N-[(1R)-1-(4-fluorophenyl)ethyl]-4-[6- (4-fluorophenyl)thieno[3,2-d]pyrimidin-4- yl]-2-methyl-piperazine-1-carboxamide::US10227357, Compound P-0606

SMILES N#Cc1cnn2c(-c3cc(NC(C)C)c(-c4nnc(N5CCN(C6CCN(C(=O)Cc7cccc8c7CN(C7CCC(=O)NC7=O)C8=O)CC6)CC5)s4)cn3)ccc2c1

InChI Key InChIKey=OFJCPJVLANPLDK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369292   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369292BDBM369292(US12528814, Example 76)
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent