BDBM369244 N-[(1S)-1-(3-chlorophenyl)ethyl]-4-[6-(2- methoxy-4-pyridyl)thieno[3,2- d]pyrimidin-4-yl]-2,2-dimethyl-piperazine- 1-carboxamide::US10227357, Compound P-0556

SMILES CC(C)Nc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(N2CCN(CCCCc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)CC2)s1

InChI Key InChIKey=WRULVEWNDYFGEE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 369244   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369244BDBM369244(US12528814, Example 28)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369244BDBM369244(US12528814, Example 28)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent