BDBM369240 N-[(1S)-1-(3-chlorophenyl)ethyl]-4-[6-[1- (cyclopropanecarbonyl)-3,6-dihydro-2H- pyridin-4-yl]thieno[3,2-d]pyrimidin-4-yl]- 2,2-dimethyl-piperazine-1-carboxamide::US10227357, Compound P-0552

SMILES CC(C)Nc1cc(-c2ccc3cc(C#N)cnn23)ncc1-c1nnc(N2CCN(C(=O)C3CCN(CC4CCN(c5ccc(-c6nn(C7CCC(=O)NC7=O)c(=O)n6C)cc5)CC4)CC3)CC2)s1

InChI Key InChIKey=SNNQBHYLIVZWNM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 369240   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369240BDBM369240(US12528814, Example 24)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 369240BDBM369240(US12528814, Example 24)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2026
Entry Details US Patent