BDBM369075 N-[4-[6-(2,4-difluorophenyl)-7H- pyrrolo[2,3-d]pyrimidin-4-yl]-3-fluoro- phenyl]cyclopropanesulfonamide::US10227357, Compound P-0340

SMILES Fc1ccc(-c2cc3c(ncnc3[nH]2)-c2ccc(NS(=O)(=O)C3CC3)cc2F)c(F)c1

InChI Key InChIKey=MOQXISQZUCPBDM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 369075   

LigandPNGBDBM369075(US10227357, Compound P-0340 | N-[4-[6-(2,4-difluor...)
Affinity DataKi:  500nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Plexxikon

US Patent
LigandPNGBDBM369075(US10227357, Compound P-0340 | N-[4-[6-(2,4-difluor...)
Affinity DataKi:  1.05E+5nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent