BDBM368580 N-(5-fluoro-1H-pyrazolo [3,4-b]pyridin-3-yl)-1- (trifluoromethyl) isoquinolin-6-amine::US10227343, Example 183

SMILES Fc1cnc2[nH]nc(Nc3ccc4c(nccc4c3)C(F)(F)F)c2c1

InChI Key InChIKey=HZRUTASRPRQDFH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368580   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandPNGBDBM368580(N-(5-fluoro-1H-pyrazolo [3,4-b]pyridin-3-yl)-1- (t...)
Affinity DataEC50:  59.5nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent