BDBM368202 US10227334, Example 2-(4-((S)-2-(azetidin-1-yl)propoxy)phenyl)-3-(3-hydroxyphenyl)-4-methyl-2H- chromen-6-ol

SMILES C[C@@H](COc1ccc(cc1)C1Oc2ccc(O)cc2C(C)=C1c1cccc(O)c1)N1CCC1

InChI Key InChIKey=MCHMIAOISTZARG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 368202   

TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM368202(US10227334, Example 2-(4-((S)-2-(azetidin-1-yl)pro...)
Affinity DataIC50: 0.900nMAssay Description:Induction of ERalpha degradation in human MCF7 cells in phenol red free RPMI medium containing 5% charcoal dextran-treated FBS incubated for 4 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM368202(US10227334, Example 2-(4-((S)-2-(azetidin-1-yl)pro...)
Affinity DataIC50: 100nMAssay Description:MCF-7 cells were adjusted to a concentration of 40,000 cells per mL in RPMI containing 10% FBS and 20 mM HEPES. 16 microliters of the cell suspension...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent