BDBM367927 3-((4-(benzo[d]thiazol-5- yl)-2-sulfamoyl-3-(1H- tetrazol-5- yl)phenyl)sulfonyl)azetidin- 1-ium 2,2,2- trifluoroacetate::US10227331, Example 114

SMILES NS(=O)(=O)c1c(ccc(-c2ccc3scnc3c2)c1-c1nnn[nH]1)S(=O)(=O)C1CNC1

InChI Key InChIKey=VOLILWYXCLWYSU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 367927   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367927(US10227331, Example 114 | 3-((4-(benzo[d]thiazol-5...)
Affinity DataIC50: 0.261nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367927(US10227331, Example 114 | 3-((4-(benzo[d]thiazol-5...)
Affinity DataIC50: 0.150nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetVIM-1 protein(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM367927(US10227331, Example 114 | 3-((4-(benzo[d]thiazol-5...)
Affinity DataIC50: 0.116nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent