BDBM3677 4-N-(3-methylphenyl)-7-N-[3-(4-methylpiperazin-1-yl)propyl]pyrido[4,3-d]pyrimidine-4,7-diamine::4-[(3-Methylphenyl)amino]-7-[[3-(4-methylpiperazin-1-yl)propyl]amino]pyrido[4,3-d]pyrimidine::pyrido[4,3-d]pyrimidine deriv. 4u

SMILES CN1CCN(CCCNc2cc3ncnc(Nc4cccc(C)c4)c3cn2)CC1

InChI Key InChIKey=ZSWVFFAVTCICJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3677   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3677(4-[(3-Methylphenyl)amino]-7-[[3-(4-methylpiperazin...)
Affinity DataIC50: 5.60nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed