BDBM367671 US10227314, Compound 2-aminopent-4-ynoic acid

SMILES NC(CC#C)C(O)=O

InChI Key InChIKey=DGYHPLMPMRKMPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367671   

TargetCystathionine gamma-lyase(Human)
Sova Pharmaceuticals

US Patent
LigandPNGBDBM367671(US10227314, Compound 2-aminopent-4-ynoic acid)
Affinity DataIC50: 2.50E+4nMAssay Description:Test compounds (from DMSO stock solutions) were added to (final concentrations) 20 ug/ml enzyme solution (human, mouse or rat recombinant CSE) plus 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetCystathionine gamma-lyase(Mouse)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM367671(US10227314, Compound 2-aminopent-4-ynoic acid)
Affinity DataIC50: 3.71E+5nMAssay Description:Inhibition of CSE in mouse RAW264.7 cells assessed as reduction in endogenous H2S level by AzMC probe based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed