BDBM367612 N-[(1S)-2-[4-[2-(4-Amino-6-chloro-2-methyl-pyrimidin-5-yl)ethyl]-1-piperidyl]-1-methyl-2-oxo-ethyl]-2-methyl-thiazole-5-carboxamide::US10227310, Example 42

SMILES C[C@H](NC(=O)c1cnc(C)s1)C(=O)N1CCC(CCc2c(N)nc(C)nc2Cl)CC1

InChI Key InChIKey=KLRWUOFULIPURB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367612   

TargetGhrelin O-acyltransferase(Human)
Eli Lilly

US Patent
LigandPNGBDBM367612(US10227310, Example 42 | N-[(1S)-2-[4-[2-(4-Amino-...)
Affinity DataIC50: 96.4nMAssay Description:Prepare test compounds in DMSO to make up a 0.2 mM stock solution. Serially dilute the stock solution in DMSO for ten concentrations with final compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetGhrelin O-acyltransferase(Human)
Eli Lilly

US Patent
LigandPNGBDBM367612(US10227310, Example 42 | N-[(1S)-2-[4-[2-(4-Amino-...)
Affinity DataIC50: 96nMAssay Description:Inhibition of human His-tagged GOAT expressed in baculovirus infected Sf9 cell membrane using desacyl-ghrelin-biotin and octanoyl-CoA as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed