BDBM367543 N-(4-(6RS)-Oxo-3-(phenylamino)-6-[(1,3-thiazol-2-ylsulfanyl)methyl]-4,5,6,7-tetrahydro-1H-indol-2-ylpyridin-2-yl)acetamide::US10227299, Example 231

SMILES CC(=O)Nc1cc(ccn1)-c1[nH]c2CC(CSc3nccs3)CC(=O)c2c1Nc1ccccc1

InChI Key InChIKey=RRRZFDNRGRLBCV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 367543   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
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US Patent
LigandPNGBDBM367543(US10227299, Example 231 | N-(4-(6RS)-Oxo-3-(phenyl...)
Affinity DataIC50: 8nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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