BDBM367541 N-4-[(6RS)-6-[(2-Methoxyethyl)sulfanyl]methyl-4-oxo-3-(phenylamino)-4,5,6,7-tetrahydro-1H-indol-2-yl]pyridin-2-ylacetamide::US10227299, Example 229

SMILES COCCSCC1Cc2[nH]c(c(Nc3ccccc3)c2C(=O)C1)-c1ccnc(NC(C)=O)c1

InChI Key InChIKey=YBRLJAVXAQQPCG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 367541   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
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US Patent
LigandPNGBDBM367541(US10227299, Example 229 | N-4-[(6RS)-6-[(2-Methoxy...)
Affinity DataIC50: 8nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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