BDBM3674 7-(Methylamino)-4-[(3-methylphenyl)amino]pyrido-[4,3-d]pyrimidine::7-N-methyl-4-N-(3-methylphenyl)pyrido[4,3-d]pyrimidine-4,7-diamine::pyrido[4,3-d]pyrimidine deriv. 4b

SMILES CNc1cc2ncnc(Nc3cccc(C)c3)c2cn1

InChI Key InChIKey=YAVCJZFLGRQKCZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 3674   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3674(7-(Methylamino)-4-[(3-methylphenyl)amino]pyrido-[4...)
Affinity DataIC50: 1.40nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed