BDBM367342 (6RS)-6-(Azidomethyl)-3-(phenylamino)-2-(pyridin-4-yl)-1,5,6,7-tetrahydro-4H-indol-4-one 32-1: [(6RS)-3-Anilino-4-oxo-2-(pyridin-4-yl)-4,5,6,7-tetrahydro-1H-indol-6-yl]methyl methanesulfonate::US10227299, Example 32

SMILES CS(=O)(=O)OCC1Cc2[nH]c(c(Nc3ccccc3)c2C(=O)C1)-c1ccncc1

InChI Key InChIKey=BZAWAAXNKFCIPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 367342   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
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US Patent
LigandPNGBDBM367342((6RS)-6-(Azidomethyl)-3-(phenylamino)-2-(pyridin-4...)
Affinity DataIC50: 9nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
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