BDBM366074 5-[4-[5-[2-(Pyridin-3-yl)ethyl]-1H-tetrazol-1-yl]phenyl]-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione::US9873683, Example 3

SMILES O=C1CC(=O)N(c2ccc(cc2)-n2nnnc2CCc2cccnc2)c2ccc3ccccc3c2N1

InChI Key InChIKey=CGLMUUHFODGYRZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 366074   

TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent
LigandPNGBDBM366074(5-[4-[5-[2-(Pyridin-3-yl)ethyl]-1H-tetrazol-1-yl]p...)
Affinity DataIC50: 380nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent