BDBM366035 N-(2-{[(4-{[3-(2H-1,3- benzodioxol-5-yl)-2- methylphenyl]methoxy}-2,6- dimethoxyphenyl)methyl]amino} ethyl)acetamide::US9872852, Example 287

SMILES COc1cc(OCc2cccc(c2C)-c2ccc3OCOc3c2)cc(OC)c1CNCCNC(C)=O

InChI Key InChIKey=HPRGLYMHZHSKBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 366035   

TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM366035(N-(2-{[(4-{[3-(2H-1,3- benzodioxol-5-yl)-2- methyl...)
Affinity DataIC50: 555nMAssay Description:All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
Go to US Patent

LigandPNGBDBM366035(N-(2-{[(4-{[3-(2H-1,3- benzodioxol-5-yl)-2- methyl...)
Affinity DataIC50: 110nMAssay Description:Inhibition of Ig-tagged PD-1 (unknown origin)/His-tagged PD-L1 (unknown origin) protein-protein interaction preincubated with PD-L1 for 15 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed