BDBM365965 N-{2-[({6-[(2-methyl-3- phenylphenyl)methoxy]pyridin-3- yl}methyl)amino]ethyl}acetamide::US9872852, Example 217

SMILES CC(=O)NCCNCc1ccc(OCc2cccc(c2C)-c2ccccc2)nc1

InChI Key InChIKey=OLDRYSNASSVDEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 365965   

TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM365965(N-{2-[({6-[(2-methyl-3- phenylphenyl)methoxy]pyrid...)
Affinity DataIC50: 555nMAssay Description:All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
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LigandPNGBDBM365965(N-{2-[({6-[(2-methyl-3- phenylphenyl)methoxy]pyrid...)
Affinity DataIC50: 110nMAssay Description:Inhibition of Ig-tagged PD-1 (unknown origin)/His-tagged PD-L1 (unknown origin) protein-protein interaction preincubated with PD-L1 for 15 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed