BDBM365904 2-(4-{[(2S)-2- (hydroxymethyl)pyrrolidin-1- yl]methyl}-3,5- dimethoxyphenoxymethyl)-6- phenylbenzonitrile::US9872852, Example 156

SMILES COc1cc(OCc2cccc(-c3ccccc3)c2C#N)cc(OC)c1CN1CCC[C@H]1CO

InChI Key InChIKey=XKPLUFKYCZERKI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365904   

TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM365904(2-(4-{[(2S)-2- (hydroxymethyl)pyrrolidin-1- yl]met...)
Affinity DataIC50: 53nMAssay Description:All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent