BDBM365900 N-[(3S)-1-({4-[(2-cyano-3- phenylphenyl)methoxy]-2,6- dimethoxyphenyl}methyl) pyrrolidin-3-yl]acetamide::US9872852, Example 152

SMILES COc1cc(OCc2cccc(-c3ccccc3)c2C#N)cc(OC)c1CN1CC[C@@H](C1)NC(C)=O

InChI Key InChIKey=JCRRGWHYBLZCAI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365900   

TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM365900(N-[(3S)-1-({4-[(2-cyano-3- phenylphenyl)methoxy]-2...)
Affinity DataIC50: 53nMAssay Description:All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent