BDBM365862 (3S)-4-{[(4-{[3-(2,3-dihydro-1,4- benzodioxin-6-yl)-2- methylphenyl]methoxy}-3- (trifluoromethyl)phenyl)methyl] amino}-3-hydroxybutanoic acid::US9872852, Example 114

SMILES Cc1c(COc2cc(CNC[C@@H](O)CC(O)=O)ccc2C(F)(F)F)cccc1-c1ccc2OCCOc2c1

InChI Key InChIKey=BXTVOBAMQXQEKX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365862   

TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM365862((3S)-4-{[(4-{[3-(2,3-dihydro-1,4- benzodioxin-6-yl...)
Affinity DataIC50: 43nMAssay Description:All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent