BDBM365624 6-[4-(furo[2,3-d]pyrimidin-4-yloxy)phenyl]-1,5-dimethylpyrimidine-2,4(1H,3H)-dione::US9868744, 9

SMILES Cc1c(-c2ccc(Oc3ncnc4occc34)cc2)n(C)c(=O)[nH]c1=O

InChI Key InChIKey=OPWNENBCRRSEBU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365624   

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM365624(6-[4-(furo[2,3-d]pyrimidin-4-yloxy)phenyl]-1,5-dim...)
Affinity DataKi:  142nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
Go to US Patent