BDBM36551 Chelator, M30::US9034303, M30

SMILES CN(CC#C)Cc1ccc(O)c2ncccc12

InChI Key InChIKey=FQFLPZZATVCNLA-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 36551   

TargetAcetylcholinesterase(Rat)
The Weizmann Institute of Science

LigandPNGBDBM36551(Chelator, M30 | US9034303, M30)
Affinity DataIC50: 1.14E+5nMpH: 7.4 T: 2°CAssay Description:Inhibition of AChE and BChE activity in rat brain homogenates using Ellman's method. More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
The Weizmann Institute of Science

LigandPNGBDBM36551(Chelator, M30 | US9034303, M30)
Affinity DataIC50: 37nMpH: 7.4 T: 2°CAssay Description:Inhibition of MAO activity in rat brain homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
TBA

US Patent
LigandPNGBDBM36551(Chelator, M30 | US9034303, M30)
Affinity DataIC50: 37nMAssay Description:MAO-A and MAO-B activity was measured using radioactive substrates. The substrate for MAO-A was 5 HT and for MAO-B was PEA. When measuring the activi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
TBA

US Patent
LigandPNGBDBM36551(Chelator, M30 | US9034303, M30)
Affinity DataIC50: 57nMAssay Description:MAO-A and MAO-B activity was measured using radioactive substrates. The substrate for MAO-A was 5 HT and for MAO-B was PEA. When measuring the activi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2015
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Rat)
Okayama University

Curated by ChEMBL
LigandPNGBDBM36551(Chelator, M30 | US9034303, M30)
Affinity DataIC50: 57nMAssay Description:Inhibition of MAO-A in rat liver homogenate using [14C]-5HT as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
The Weizmann Institute of Science

LigandPNGBDBM36551(Chelator, M30 | US9034303, M30)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of MAO-B in rat liver homogenate using [14C]-phenylethylamine as substrate preincubated for 30 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM36551(Chelator, M30 | US9034303, M30)
Affinity DataIC50: 1.60E+3nMAssay Description:Irreversible inhibition of BACE-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
TBA

US Patent
LigandPNGBDBM36551(Chelator, M30 | US9034303, M30)
Affinity DataIC50: 5.70E+4nMAssay Description:Mixed type inhibition of MAOA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
TBA

US Patent
LigandPNGBDBM36551(Chelator, M30 | US9034303, M30)
Affinity DataIC50: 1.50E+3nMAssay Description:Mixed type inhibition of MAOB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
TBA

US Patent
LigandPNGBDBM36551(Chelator, M30 | US9034303, M30)
Affinity DataIC50: 6.20E+3nMAssay Description:Irreversible inhibition of MAOA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM36551(Chelator, M30 | US9034303, M30)
Affinity DataIC50: 1.80E+3nMAssay Description:Irreversible inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
TBA

US Patent
LigandPNGBDBM36551(Chelator, M30 | US9034303, M30)
Affinity DataIC50: 1.02E+4nMAssay Description:Irreversible inhibition of MAOB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed