BDBM365391 2-(4-(4-acetyl-2-carbamoylpiperazin-1-yl)phenylamino)-4-(cyclopropylamino)pyrimidine-5-carboxamide::US10533001, Example 55::US11414410, Example 55::US9868729, Example 55
SMILES CC(=O)N1CCN(C(C1)C(N)=O)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
InChI Key InChIKey=PSSHWNRPVJAAGC-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 365391
Affinity DataIC50: 55nMAssay Description:SYK tyrosine phosphorylation activity is measured using the LANCE Technology developed by Perkin Elmer Life and Analytical Sciences (Boston, Mass.). ...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Syk and JAK: The activity of a specified compound as an inhibitor of a JAK kinase may be assessed in vitro or in vivo. In some embodiments, the activ...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:The kinase reaction is performed in a black U-bottom 96-well microtitre plate. The final reaction volume is 50 μL and contains a final concentra...More data for this Ligand-Target Pair